NEET Solved Paper 2017 Question 37

Question: Thalassemia and sickle cell anemia are caused due to a problem in globin molecule synthesis. Select the correct statement.

Options:

A) Sickle cell anemia is due to a quantitative problem of globin molecules

B) Both are due to a qualitative defect in globin chain synthesis

C) Both are due to a quantitative defect in globin chain synthesis

D) Thalassemia is due to less synthesis of globin molecules

Show Answer

Answer:

Correct Answer: D

Solution:

  • Thalassemia is characterized by a quantitative defect in the synthesis of globin chains, leading to an imbalance in the production of alpha or beta globin chains. Sickle cell anemia, on the other hand, is caused by a qualitative defect due to a specific mutation in the beta-globin gene, resulting in the production of abnormal hemoglobin (HbS).