Neet Solved Paper 2015 Question 54

Question: Which one of the following statements is incorrect?

Options:

A) A competitive inhibitor reacts reversibly with the enzyme to form an enzyme-inhibitor.

B) In competitive inhibition the inhibitor molecule is not chemically changed by the enzyme.

C) The competitive inhibitor does not affect the rate of breakdown of the enzyme-substrate complex.

D) The presence of the competitive inhibitor decreases the km of the enzyme for the substrate.

Show Answer

Answer:

Correct Answer: D

Solution:

  • In competitive inhibition, the inhibitor competes with the substrate for binding to the active site of the enzyme. This type of inhibition increases the apparent Km (Michaelis constant) for the substrate because a higher concentration of substrate is required to achieve the same rate of reaction. However, it does not affect the Vmax (maximum rate of reaction) because the inhibition can be overcome by increasing the substrate concentration.